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Acetyl-CoA inhibits pyruvate dehydrogenase, while succinyl-CoA inhibits alpha-ketoglutarate dehydrogenase and citrate synthase

The resulting mixture was centrifuged, the supernatant was removed, and the sample was subjected to the LC-MS/MS analysis without further manipulation

Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study